Comparison of transdermal nitrate and isosorbide dinitrate in chronic stable angina.
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چکیده
منابع مشابه
Evaluation of nitroglycerin in angina in patients on isosorbide dinitrate.
Seventeen male patients with angina pectoris due to coronary artery disease who had not received long-acting nitrites for at least 1 mo prior to this study were evaluated in a double-blind crossover study to investigate whether the presence of isosorbide dinitrate interfered with the effective response of exercise-induced angina to nitroglycerin administered sublingually. There was no significa...
متن کاملSublingual isosorbide dinitrate therapy versus sublingual acebo in angina pectoris.
A double-blind crossover study comparing the effects of 5 mg of isosorbide dinitrate given sublingually four times daily for 4 weeks to those of a placebo also administered sublingually four times daily for 4 weeks was performed on 20 male patients with classical exeitional angina pectoris due to coronary artery disease. Isosorbide dinitrate, compared to placebo, significantly reduced the numbe...
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26. Bleifeld W, Mathey D, Hanrath P, Buss H, Effert S: Infarct size estimated from serial serum creatine phosphokinase in relation to left ventricular hemodynamics. Circulation 55: 303, 1977 27. Humphries JO, Pitt B, Griffith LSC, Ducci HH, Achuff S, Baird M, Schulze RA Jr: Coronary angiography and left ventriculography in survivors of transmural and subendocardial myocardial infarction. Circul...
متن کاملAcute haemodynamic comparison of amrinone and pirbuterol in chronic heart failure. Additional effects of isosorbide dinitrate.
A randomised, within patient comparison was made in patients with severe chronic heart failure, to study the acute haemodynamic effects of oral agents which have inotropic and vasodilator properties. A non-glycosidic non-adrenergic positive inotropic agent with vasodilator properties (amrinone) was compared with a beta-agonist which has vasodilator and positive inotropic effects (pirbuterol). T...
متن کاملClinical and circulatory effects of isosorbide dinitrate. Comparison with nitroglycerin.
In order to resolve current controversies on isosorbide dinitrate (ISDN), we employed a particularly sensitive testing protocol to evaluate effects of sublingual ISDN and nitroglycerin on the exercise capacity of patients with angina. Ten minutes after ISDN 21 of 23 patients exercised longer (average 2.7 minutes, P < 0.001) than after placebo. Benefit was evident in only a minority of patients ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1986
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1986.tb02873.x